SB-258585, [N-Methyl-3H]-

Catalog>7TM>5HT (Serotonin)>[3H]SB-258585


Product Number: NML3H1025
Alternate Name: NA
Specific Activity: 75-87 Ci/mmol
CAS Number (Parent): 1216468-02-8
Shipping Conditions: Shipped on dry ice
Storage Conditions: -20ºC, in ethanol

Information: Potent and selective 5-HT6 receptor antagonist radioligand.

5-HT6 receptor binding sites in schizophrenia and following antipsychotic drug administration: autoradiographic studies with 125I-SB-258585.
S.Z. East, P.W. Burnet, R.A. Leslie, J.C. Roberts and P.J. Harrison (2002) Synapse 45 (3): 191–199. PMID: 12112397

Characterization of 125I-SB-258585 binding to human recombinant and native 5-HT6 receptors in rat, pig and human brain tissue.
W.D. Hirst, J.A. Minton, S.M. Bromide, S.F. Moss, A.J. Latter, G. Riley, C. Rutledge, D.N. Middlemiss and G.W. Price (2000) British Journal of Pharmacology 130 (7): 1597–1605. PMID: 10928963

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