Advancing Your Research

METIS Laboratories specializes in radioligand binding assays, receptor occupancy determinations, autoradiography, small animal imaging, and custom radiolabeling and synthesis—all aspects of R&D radiotracer services.

Advancing Your Research

METIS Laboratories specializes in radioligand binding assays, receptor occupancy determinations, autoradiography, small animal imaging, and custom radiolabeling and synthesis—all aspects of R&D radiotracer services.

Advancing Your Research

METIS Laboratories specializes in radioligand binding assays, receptor occupancy determinations, autoradiography, small animal imaging, and custom radiolabeling and synthesis—all aspects of R&D radiotracer services.

Featured Services

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in vivo ADME

Pre-clinical in vivo ADME studies are an important component of the drug development process which is designed to investigate the Absorption, Distribution, Metabolism, and Excretion (ADME) of your novel compounds.

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Radioligand Binding Assays

METIS Labs can radiolabel your small molecule, antibody, or protein to screen for interactions with thousands of human proteins immobilized on microarray chips.

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Autoradiography

Autoradiography can be used to determine the anatomical distribution of binding sites of a radiolabeled drug (receptor distribution), receptor occupancy of a competing unlabeled drug given either in vitro or ex vivo & biodistribution of radiolabeled drug among the organs.

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Bioanalytical Services (LC/MS)

METIS Labs' offers state-of-the-art bioanalytical testing facility to support detection of compounds at all stages of development, from drug discovery, to nonclinical and clinical studies.

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in vitro BA/BE Studies

METIS Labs' provides in vitro Release Testing (IVRT), in vitro Permeation Testing (IVPT) as well as Cellular Protection Assays to establish product bioequivalence to enable succesful NCE, ANDA or 505(b)(2) filing.

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Cell & Gene Therapy

We provide in vitro, in vivo, and analytical support in compliance with GMP guidelines to attain an IND, ANDA or BLA faster.

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In Vivo ADME

Pre-clinical in vivo ADME studies are an important component of the drug development process which is designed to investigate the Absorption, Distribution, Metabolism, and Excretion (ADME) of your novel compounds.

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Proteomic Profiling

METIS Labs can radiolabel your small molecule, antibody, or protein to screen for interactions with thousands of human proteins immobilized on microarray chips.

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Profiling & Screening Services

in vitro pharmacological profiling is being used earlier in the drug discovery process to identify desirable & undesirable off- target effects.

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Functional Assays

GTP binding is a method used to study the distribution and functional activation of seven-transmembrane, heterotrimeric G protein coupled family (GPCRs) receptors.

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Autoradiography

Autoradiography can be used to determine the anatomical distribution of binding sites of a radiolabeled drug (receptor distribution), receptor occupancy of a competing unlabeled drug given either in vitro or ex vivo & biodistribution of radiolabeled drug among the organs.

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Antibody Radiolabeling & Screening

One way the immune system attacks foreign substances in the body is by making large numbers of antibodies.

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