5-HT (Serotonin) Receptor Radiochemicals

Catalog>7TM>5HT (Serotonin)

5-Hydroxytryptamine (5-HT, serotonin) is a monoamine neurotransmitter synthesized from L-tryptophan in serotonergic neurons and enterochromaffin cells of the gastrointestinal tract. 5-HT acts at serotonin receptors, which have been classified into seven groups (5-HT1-7) based on their pharmacological profiles.

Except for the 5-HT3 receptor, which is a ligand-gated ion channel, 5-HT receptors belong to the G-protein-coupled receptor (GPCR) superfamily. The 5-HT1, 5-HT2 and 5-HT6 receptor groups have been further subdivided. In the central nervous system, serotonin has an important role in the regulation of mood, emesis, sexuality, sleep and appetite. Abnormalities in serotonergic function have been implicated in many disease states such as depression, anxiety, schizophrenia and migraine.

MDL100907 Cat Button

Important: To receive radiochemicals please submit your Department of Health Radioactive Materials License to radsupport@metislabs.com (or fax to: 516.825.5129, ATTN Rad Support) to ensure rapid receipt of your radiochemical order.