Acetylcholine Nicotinic Radiochemicals
Nicotinic Acetylcholine Receptors, or nAChRs, are ligand-gated ion channels (LGICs) that modulate cell membrane potentials that respond to the neurotransmitter acetylcholine. They are considered cholinergic receptors, since they respond to acetylcholine. Nicotinic receptors get their name from nicotine, which does not stimulate the muscarinic acetylcholine receptor, but instead selectively binds to the nicotinic receptor. Each receptor is composed of pentameric combinations of subunits (α1-10, β1-4, δ, ε and γ).