METIS Labs is a Preclinical Contract Research & Development organization specializing in radioligand binding assays, receptor occupancy determinations, autoradiography, ADME-PK, small animal imaging, custom radiolabeling & synthesis , and development of mouse models for cancer research — and all other aspects of R&D radiotracer services.
Radioligand binding assays are used to characterize the binding of a drug to its target receptor. They can provide information on both the affinity and mode of interaction of the drug with its receptor.
Autoradiography can be used to determine anatomical distribution of binding sites of a radiolabeled drug (receptor distribution), receptor occupancy of a competing unlabeled drug given either in vitro or ex vivo & biodistribution of radiolabeled drug among the organs.
One way the immune system attacks foreign substances in the body is by making large numbers of antibodies. An antibody is a protein that sticks to a specific protein called an antigen. Antibodies circulate throughout the body until they find and attach to the antigen. Once attached, they can recruit other parts of the immune system to destroy the cells containing the antigen.
CUSTOM RADIOSYNTHESIS & RADIOLABELING
METIS Labs can provide you custom radiolabeling and custom radiosynthesis of your small molecules, peptides, antibodies and proteins. METIS Labs’ will confidentially advise you on the appropriate labeling technique to ensure high specific activity and retention of the molecular structure which is essential for the success of radiometric assays.
Contact us to discuss your research needs and how METIS Labs can help accomplish your scientific goals.